PITTSBURGH -- Ray Graham ran for 201 yards and three touchdowns as Pittsburgh kicked off new coach Todd Graham's tenure with a 35-16 victory over Buffalo on Saturday night.

Tino Sunseri threw for 179 yards and a score for the Panthers, who needed a full half to find their legs while playing in their coach's uptempo system.

Pitt broke it open in the third quarter behind Ray Graham, who scored on runs of 3 and 5 yards to help Pitt get some breathing room. He later added a 1-yard plunge to complete the second 200-yard game of his career.

Cincinnati transfer Chazz Anderson threw for 276 yards and ran for a touchdown for Buffalo, but also threw a costly interception in the third quarter that allowed Pittsburgh to finally break loose. Branden Oliver ran for a career-high 114 yards and a score for the Bulls.